Photocollection

Publications

2010 | 2009 |2008| 2007 | 2006 | 2005 | 2004 | 2002/2003 | 2001 | 2000 | 1998/1999 | 1996/1997

2010

Xuan NT, Shumilina E, Gulbins E, Gu S, Götz F, Lang F.
Triggering of dendritic cell apoptosis by xanthohumol.
Mol Nutr Food Res. 2010 Jul;54 Suppl 2:S214-24.

Müller P, Müller-Anstett M, Wagener J, Gao Q, Kaesler S, Schaller M, Biedermann T, Götz F.
Staphylococcus aureus lipoprotein SitC co-localizes with TLR2 in murine keratinocytes and elicits intracellular TLR2 accumulation.
Infect Immun. 2010 Aug 2. [Epub ahead of print]

Lin P, Hu T, Hu J, Yu W, Han C, Zhang J, Qin G, Yu K, Götz F, Shen X, Jiang H, Qu D.
Characterization of peptide deformylase homologs from Staphylococcus epidermidis.
Microbiology. 2010 Jul 23. [Epub ahead of print]

Hirschhausen N, Schlesier T, Schmidt MA, Götz F, Peters G, Heilmann C.
A Novel Staphylococcal Internalization Mechanism Involves the Major Autolysin Atl and Heat Shock Cognate Protein Hsc70 as Host Cell Receptor.
Cell Microbiol. 2010 Jul 14. [Epub ahead of print]

Xuan NT, Shumilina E, Schmid E, Bhavsar SK, Rexhepaj R, Götz F, Gulbins E, Lang F.
Role of acidic sphingomyelinase in thymol-mediated dendritic cell death.
Mol Nutr Food Res. 2010 Jul 5. [Epub ahead of print]

Shumilina E, Xuan NT, Schmid E, Bhavsar SK, Szteyn K, Gu S, Götz F, Lang F.
Zinc induced apoptotic death of mouse dendritic cells.
Apoptosis. 2010 Jun 22. [Epub ahead of print]

Yu W, Herbert S, Graumann PL, Götz F.
Contribution of SMC (structural maintenance of chromosomes) and SpoIIIE to chromosome segregation in Staphylococci.
J Bacteriol. 2010 Aug;192(15):4067-73. Epub 2010 Jun 4.

Volz T, Nega M, Buschmann J, Kaesler S, Guenova E, Peschel A, Röcken M, Götz F, Biedermann T.
Natural Staphylococcus aureus-derived peptidoglycan fragments activate NOD2 and act as potent costimulators of the innate immune system exclusively in the presence of TLR signals.
FASEB J. 2010 Jun 3. [Epub ahead of print]

Xuan NT, Shumilina E, Nasir O, Bobbala D, Götz F, Lang F.
Stimulation of mouse dendritic cells by Gum Arabic.
Cell Physiol Biochem. 2010;25(6):641-8. Epub 2010 May 18.

Manosroi A, Khanrin P, Lohcharoenkal W, Werner RG, Götz F, Manosroi W, Manosroi J.
Transdermal absorption enhancement through rat skin of gallidermin loaded in niosomes.
Int J Pharm. 2010 Jun 15;392(1-2):304-10. Epub 2010 Apr 8.

Zoll S, Pätzold B, Schlag M, Götz F, Kalbacher H, Stehle T.
Structural basis of cell wall cleavage by a staphylococcal autolysin.
PLoS Pathog. 2010 Mar 12;6(3):e1000807.

Manosroi J, Khositsuntiwong N, Manosroi W, Götz F, Werner RG, Manosroi A.
Enhancement of transdermal absorption, gene expression and stability of tyrosinase plasmid (pMEL34)-loaded elastic cationic niosomes: potential application in vitiligo treatment.
J Pharm Sci. 2010 Aug;99(8):3533-41.

Herbert S, Ziebandt AK, Ohlsen K, Schäfer T, Hecker M, Albrecht D, Novick R, Götz F.
Repair of global regulators in Staphylococcus aureus 8325 and comparative analysis with other clinical isolates.
Infect Immun. 2010 Jun;78(6):2877-89. Epub 2010 Mar 8.

Gaupp R, Schlag S, Liebeke M, Lalk M, Götz F.
Advantage of upregulation of succinate dehydrogenase in Staphylococcus aureus biofilms.
J Bacteriol. 2010 May;192(9):2385-94. Epub 2010 Mar 5.

Shimada T, Park BG, Wolf AJ, Brikos C, Goodridge HS, Becker CA, Reyes CN, Miao EA, Aderem A, Götz F, Liu GY, Underhill DM.
Staphylococcus aureus evades lysozyme-based peptidoglycan digestion that links phagocytosis, inflammasome activation, and IL-1beta secretion.
Cell Host Microbe. 2010 Jan 21;7(1):38-49.

Manosroi A, Khanrin P, Werner RG, Götz F, Manosroi W, Manosroi J.
Entrapment enhancement of peptide drugs in niosomes.
J Microencapsul. 2010 May;27(3):272-80.

Xuan NT, Shumilina E, Qadri SM, Götz F, Lang F.
Effect of thymoquinone on mouse dendritic cells.
Cell Physiol Biochem. 2010;25(2-3):307-14. Epub 2010 Jan 12.

Schlag M, Biswas R, Krismer B, Kohler T, Zoll S, Yu W, Schwarz H, Peschel A, Götz F.
Role of staphylococcal wall teichoic acid in targeting the major autolysin Atl.
Mol Microbiol. 2010 Feb;75(4):864-73. Epub 2010 Jan 25.

Daly KM, Upton M, Sandiford SK, Draper LA, Wescombe PA, Jack RW, O'Connor PM, Rossney A, Götz F, Hill C, Cotter PD, Ross RP, Tagg JR.
Production of the Bsa lantibiotic by community-acquired Staphylococcus aureus strains.
J Bacteriol. 2010 Feb;192(4):1131-42. Epub 2009 Dec 18.

Götz F, Hacker J, Hecker M.
Pathophysiology of staphylococci in the post-genomic era.
Int J Med Microbiol. 2010 Feb;300(2-3):75. No abstract available.

Rosenstein R, Götz F.
Genomic differences between the food-grade Staphylococcus carnosus and pathogenic staphylococcal species.
Int J Med Microbiol. 2010 Feb;300(2-3):104-8. Epub 2009 Oct 9. Review.

Schmaler M, Jann NJ, Götz F, Landmann R.
Staphylococcal lipoproteins and their role in bacterial survival in mice.
Int J Med Microbiol. 2010 Feb;300(2-3):155-60. Epub 2009 Oct 4. Review.

2009

Small-colony variant selection as a survival strategy for Staphylococcus aureus in the presence of Pseudomonas aeruginosa.
Biswas L, Biswas R, Schlag M, Bertram R, Götz F.
Appl Environ Microbiol. 2009 Nov;75(21):6910-2. Epub 2009 Aug 28.

Biswas L, Biswas R, Nerz C, Ohlsen K, Schlag M, Schäfer T, Lamkemeyer T, Ziebandt AK, Hantke K, Rosenstein R, Götz F.
Role of the twin-arginine translocation pathway in Staphylococcus.
J Bacteriol. 2009 Oct;191(19):5921-9. Epub 2009 Jul 24.

Senyürek I, Paulmann M, Sinnberg T, Kalbacher H, Deeg M, Gutsmann T, Hermes M, Kohler T, Götz F, Wolz C, Peschel A, Schittek B.
Dermcidin-derived peptides show a different mode of action than the cathelicidin LL-37 against Staphylococcus aureus.
Antimicrob Agents Chemother. 2009 Jun;53(6):2499-509. Epub 2009 Apr 13.

Manosroi A, Khositsuntiwong N, Götz F, Werner RG, Manosroi J.
Transdermal enhancement through rat skin of luciferase plasmid DNA loaded in elastic nanovesicles.
J Liposome Res. 2009;19(2):91-8.

Schmaler M, Jann NJ, Ferracin F, Landolt LZ, Biswas L, Götz F, Landmann R.
Lipoproteins in Staphylococcus aureus mediate inflammation by TLR2 and iron-dependent growth in vivo.
J Immunol. 2009 Jun 1;182(11):7110-8.

Sopjani M, Föller M, Haendeler J, Götz F, Lang F.
Silver ion-induced suicidal erythrocyte death.
J Appl Toxicol. 2009 Aug;29(6):531-6.

Xuan NT, Shumilina E, Matzner N, Zemtsova IM, Biedermann T, Goetz F, Lang F.
Ca2+-dependent functions in peptidoglycan-stimulated mouse dendritic cells.
Cell Physiol Biochem. 2009;24(3-4):167-76. Epub 2009 Aug 3.

Fleury B, Kelley WL, Lew D, Götz F, Proctor RA, Vaudaux P.
Transcriptomic and metabolic responses of Staphylococcus aureus exposed to supra-physiological temperatures.
BMC Microbiol. 2009 Apr 22;9:76.

Rosenstein R, Nerz C, Biswas L, Resch A, Raddatz G, Schuster SC, Götz F.
Genome analysis of the meat starter culture bacterium Staphylococcus carnosus TM300.
Appl Environ Microbiol. 2009 Feb;75(3):811-22.

Bourgeois I, Camiade E, Biswas R, Courtin P, Gibert L, Götz F, Chapot-Chartier MP, Pons JL, Pestel-Caron M.
Characterization of AtlL, a bifunctional autolysin of Staphylococcus lugdunensis with N-acetylglucosaminidase and N-acetylmuramoyl-l-alanine amidase activities.
FEMS Microbiol Lett. 2009 Jan;290(1):105-13.

Föller M, Biswas R, Mahmud H, Akel A, Shumilina E, Wieder T, Goetz F, Lang F.
Effect of peptidoglycans on erythrocyte survival.
Int J Med Microbiol. 2009 Jan;299(1):75-85.

2008

Wang K, Mahmud H, Föller M, Biswas R, Lang KS, Bohn E, Götz F, Lang F.
Lipopeptides in the triggering of erythrocyte cell membrane scrambling.
Cell Physiol Biochem. 2008;22(5-6):381-6.

Schlag S, Fuchs S, Nerz C, Gaupp R, Engelmann S, Liebeke M, Lalk M, Hecker M, Götz F.
Characterization of the oxygen-responsive NreABC regulon of Staphylococcus aureus.
J Bacteriol. 2008 Dec;190(23):7847-58.

Zell C, Resch M, Rosenstein R, Albrecht T, Hertel C, Götz F.
Characterization of toxin production of coagulase-negative staphylococci isolated from food and starter cultures.
Int J Food Microbiol. 2008 Oct 31;127(3):246-51.

Parcina M, Wendt C, Goetz F, Zawatzky R, Zähringer U, Heeg K, Bekeredjian-Ding I.
Staphylococcus aureus-induced plasmacytoid dendritic cell activation is based on an IgG-mediated memory response.
J Immunol. 2008 Sep 15;181(6):3823-33.

Kraus D, Herbert S, Kristian SA, Khosravi A, Nizet V, Götz F, Peschel A.
The GraRS regulatory system controls Staphylococcus aureus susceptibility to antimicrobial host defenses.
BMC Microbiol. 2008 Jun 2;8:85.

Kristian SA, Birkenstock TA, Sauder U, Mack D, Götz F, Landmann R.
Biofilm formation induces C3a release and protects Staphylococcus epidermidis from IgG
and complement deposition and from neutrophil-dependent killing.
J Infect Dis. 2008 Apr 1;197(7):1028-35.

Weidenmaier C, Kokai-Kun JF, Kulauzovic E, Kohler T, Thumm G, Stoll H, Götz F, Peschel A.
Differential roles of sortase-anchored surface proteins and wall teichoic acid in Staphylococcus aureus nasal colonization.
Int J Med Microbiol. 2008 Jul;298(5-6):505-13.

Leibig M, Krismer B, Kolb M, Friede A, Götz F, Bertram R.
Marker removal in staphylococci via Cre recombinase and different lox sites.
Appl Environ Microbiol. 2008 Mar;74(5):1316-23.

Hall AJ, Morroll S, Tighe P, Götz F, Falcone FH.
Human chitotriosidase is expressed in the eye and lacrimal gland and has an antimicrobial spectrum different from lysozyme.
Microbes Infect. 2008 Jan;10(1):69-78.

2007

Gust AA, Biswas R, Lenz HD, Rauhut T, Ranf S, Kemmerling B, Götz F, Glawischnig E, Lee J, Felix G, Nürnberger T.
Bacteria-derived peptidoglycans constitute pathogen-associated molecular patterns triggering innate immunity in Arabidopsis.
J Biol Chem. 2007 Nov 2;282(44):32338-48.

Schlag S, Nerz C, Birkenstock TA, Altenberend F, Götz F.
Inhibition of staphylococcal biofilm formation by nitrite.
J Bacteriol. 2007 Nov;189(21):7911-9.

Herbert S, Bera A, Nerz C, Kraus D, Peschel A, Goerke C, Meehl M, Cheung A, Götz F.
Molecular basis of resistance to muramidase and cationic antimicrobial peptide activity of lysozyme in staphylococci.
PLoS Pathog. 2007 Jul 27;3(7):e102.

Fedtke I, Mader D, Kohler T, Moll H, Nicholson G, Biswas R, Henseler K, Götz F, Zähringer U, Peschel A.
A Staphylococcus aureus ypfP mutant with strongly reduced lipoteichoic acid (LTA) content:
LTA governs bacterial surface properties and autolysin activity.
Mol Microbiol. 2007 Aug;65(4):1078-91.

Becker K, Bierbaum G, von Eiff C, Engelmann S, Götz F, Hacker J, Hecker M, Peters G, Rosenstein R, Ziebuhr W. (2007)
Understanding the physiology and adaptation of staphylococci: a post-genomic approach.
Int J Med Microbiol. 2007 Nov;297(7-8):483-501.

Meehl M, Herbert S, Götz F, Cheung A. (2007)
Interaction of the GraRS two-component system with the VraFG ABC transporter to support
vancomycin-intermediate resistance in Staphylococcus aureus.
Antimicrob Agents Chemother. 2007 Aug;51(8):2679-89

Kraus D, Kalbacher H, Buschmann J, Berger-Bachi B, Götz F, Peschel A. (2007)
Muropeptide modification-amidation of peptidoglycan D-glutamate does not affect the proinflammatory activity of Staphylococcus aureus.
Infect Immun. 75(4): 2084-7

Wu CY, Chen CL, Lee YH, Cheng YC, Wu YC, Shu HY, Götz F, Liu ST. (2007)
Nonribosomal synthesis of fengycin on an enzyme complex formed by fengycin synthetases.
J Biol Chem. 282(8): 5608-16

Kempe DS, Akel A, Lang PA, Hermle T, Biswas R, Muresanu J, Friedrich B, Dreischer P, Wolz C, Schumacher U, Peschel A, Götz F, Doring G, Wieder T, Gulbins E, Lang F. (2007)
Suicidal erythrocyte death in sepsis.
J Mol Med. 85(3): 269-77
2006

Voggu L, Schlag S, Biswas R, Rosenstein R, Rausch C, Götz F. (2006)
Microevolution of cytochrome bd oxidase in Staphylococci and its implication in resistance to respiratory toxins released by Pseudomonas.
J Bacteriol. 188(23): 8079-86.

Bera, A., Biswas, R., Herbert, S., and Götz, F. (2006) The presence of peptidoglycan O-acetyltransferase in various staphylococcal species correlates with lysozyme resistance and pathogenicity. Infect Immun 74 : 4598-4604.

Biswas, R., Voggu, L., Simon, U.K., Hentschel, P., Thumm, G., and Götz, F. (2006) Activity of the major staphylococcal autolysin Atl. FEMS Microbiol Lett 259 : 260-268.

Clauditz, A., Resch, A., Wieland, K.P., Peschel, A., and Götz, F. (2006) Staphyloxanthin plays a role in the fitness of Staphylococcus aureus and its ability to cope with oxidative stress. Infect Immun 74 : 4950-4953 .

Hashimoto, M., Tawaratsumida, K., Kariya, H., Kiyohara, A., Suda, Y., Krikae, F., Kirikae, T., and Götz, F. (2006) Not Lipoteichoic Acid but Lipoproteins Appear to Be the Dominant Immunobiologically Active Compounds in Staphylococcus aureus . J Immunol 177 : 3162-3169.

Resch, A., Leicht, S., Saric, M., Pasztor, L., Jakob, A., Götz, F., and Nordheim, A. (2006) Comparative proteome analysis of Staphylococcus aureus biofilm and planktonic cells and correlation with transcriptome profiling. Proteomics 6 : 2327.

 
2005

Bera, A., Herbert, S., Jakob, A., Vollmer, W., and Götz, F. (2005) Why are pathogenic staphylococci so lysozyme resistant? The peptidoglycan O-acetyltransferase OatA is the major determinant for lysozyme resistance of Staphylococcus aureus . Mol Microbiol 55 : 778-787.

Kropec, A., Maira-Litran, T., Jefferson, K.K., Grout, M., Cramton, S.E., Götz, F., Goldmann, D.A., and Pier, G.B. (2005) Poly-N-acetylglucosamine production in Staphylococcus aureus is essential for virulence in murine models of systemic infection. Infect Immun 73 : 6868-6876.

Pelz, A., Wieland, K.P., Putzbach, K., Hentschel, P., Albert, K., and Götz, F. (2005) Structure and biosynthesis of staphyloxanthin from Staphylococcus aureus . J Biol Chem 280 : 32493-32498.

Resch, A., Fehrenbacher, B., Eisele, K., Schaller, M., and Götz, F . (2005a) Phage release from biofilm and planktonic Staphylococcus aureus cells. FEMS Microbiol Lett 252 : 89-96.

Resch, A., Rosenstein, R., Nerz, C., and Götz, F. (2005b) Differential gene expression profiling of Staphylococcus aureus cultivated under biofilm and planktonic conditions. Appl Environ Microbiol 71 : 2663-2676.

Stoll, H., Dengjel, J., Nerz, C., and Götz, F. (2005) Staphylococcus aureus deficient in lipidation of prelipoproteins is attenuated in growth and immune activation. Infect Immun 73 : 2411-2423.

Tormo, M.A., Knecht, E., Götz, F., Lasa, I., and Penades, J.R. (2005) Bap-dependent biofilm formation by pathogenic species of Staphylococcus : evidence of horizontal gene transfer? Microbiology 151 : 2465-2475.

 
2004

Cramton, S., and Götz, F. (2004) Biofilm development in Staphylococcus . In Microbial Biofilms . Ghannoum, M.A. and OToole, G.A. (eds). Washington, DC.: ASM Press, pp. 64-84.

Fedtke, I., Götz, F., and Peschel, A. (2004) Bacterial evasion of innate host defenses - the Staphylococcus aureus lesson. Int J Med Microbiol 294 : 189-194.

Götz, F. (2004a) Hyicolysin. In Handbook of proteolytic enzymes 2 nd edition : Elsevier Ltd, pp. 456-458.

Götz, F. (2004b) Staphylococci in colonization and disease: prospective targets for drugs and vaccines. Curr Opin Microbiol 7 : 477-487.

Götz, F., Bannerman, T., and Schleifer, K.H. (2004) The Genera Staphylococcus and Macrococcus . In : The Procaryotes . Vol. Release 3.17. Dworkin, M. (ed): Springer, New York, pp. 92,.

Kamps, A., Achebach, S., Fedtke, I., Unden, G., and Götz, F . (2004) Staphylococcal NreB: an O-sensing histidine protein kinase with an O-labile iron-sulphur cluster of the FNR type. Mol Microbiol 52 : 713-723.

Kristian, S.A., Golda, T., Ferracin, F., Cramton, S.E., Neumeister, B., Peschel, A., Götz, F., and Landmann, R . (2004) The ability of biofilm formation does not influence virulence of Staphylococcus aureus and host response in a mouse tissue cage infection model. Microb Pathog 36 : 237-245.

Schmollinger, M., Fischer, I., Nerz, C., Pinkenburg, S., Götz, F., Kaufmann, M., Lange, K.J., Reuter, R., Rosenstiel, W., and Zell, A . (2004) ParSeq: searching motifs with structural and biochemical properties. Bioinformatics 20 : 1459-1461.

Wieland, H., Götz, F., and Neumeister, B. (2004) Phagosomal acidification is not a prerequisite for intracellular multiplication of Legionella pneumophila in human monocytes. J Infect Dis 189 : 1610-1614.

 
2002/2003

Collins, L.V., Kristian, S.A., Weidenmaier, C., Faigle, M., Van Kessel, K.P., Van Strijp, J.A., Götz, F., Neumeister, B., and Peschel, A . (2002) Staphylococcus aureus strains lacking D-alanine modifications of teichoic acids are highly susceptible to human neutrophil killing and are virulence attenuated in mice. J Infect Dis 186 : 214-219.

Fedtke, I., Kamps, A., Krismer, B., and Götz, F. (2002) The nitrate reductase and nitrite reductase operons and the narT gene of Staphylococcus carnosus are positively controlled by the novel two-component system NreBC. J Bacteriol 184 : 6624-6634.

Francois, P., Tu Quoc, P.H., Bisognano, C., Kelley, W.L., Lew, D.P., Schrenzel, J., Cramton, S.E., Götz, F., and Vaudaux, P. (2003) Lack of biofilm contribution to bacterial colonisation in an experimental model of foreign body infection by Staphylococcus aureus and Staphylococcus epidermidis . FEMS Immunol Med Microbiol 35 : 135-140.

Götz, F. (2002a) Den Wettlauf gegen die Bakterien gewinnen. In BMBF Newsletter . Vol. 5, pp. 6-8.

Götz, F. (2002b) Staphylococcus and biofilms. Mol Microbiol 43 : 1367-1378.

Jefferson, K.K., Cramton, S.E., Götz, F., and Pier, G.B. (2003) Identification of a 5-nucleotide sequence that controls expression of the ica locus in Staphylococcus aureus and characterization of the DNA-binding properties of IcaR. Mol Microbiol 48 : 889-899.

Kies, S., Vuong, C., Hille, M., Peschel, A., Meyer, C., Götz, F., and Otto, M. (2003) Control of antimicrobial peptide synthesis by the agr quorum sensing system in Staphylococcus epidermidis : activity of the lantibiotic epidermin is regulated at the level of precursor peptide processing. Peptides 24 : 329-338.

Kristian, S.A., Lauth, X., Nizet, V., Götz, F., Neumeister, B., Peschel, A., and Landmann, R. (2003) Alanylation of teichoic acids protects Staphylococcus aureus against Toll-like receptor 2-dependent host defense in a mouse tissue cage infection model. J Infect Dis 188 : 414-423.

Nieuwenhuizen, W.F., van Leeuwen, S., Götz, F., and Egmond, M.R . (2002) Synthesis of a novel fluorescent ceramide analogue and its use in the characterization of recombinant ceramidase from Pseudomonas aeruginosa PA01. Chem Phys Lipids 114 : 181-191.

Nieuwenhuizen, W.F., van Leeuwen, S., Jack, R.W., Egmond, M.R., and Götz, F. (2003) Molecular cloning and characterization of the alkaline ceramidase from Pseudomonas aeruginosa PA01. Protein Expr Purif 30 : 94-104.

 
2001

Braun, V., and Götz, F. , (eds) (2001) Microbial fundamentals of biotechnology. Weinheim: WILEY-VCH Verlag GmbH.

Cramton, S.E., Gerke, C., and Götz, F. (2001a) In vitro methods to study staphylococcal biofilm formation. Methods Enzymol 336 : 239-255.

Cramton, S.E., Ulrich, M., Götz, F., and Döring, G. (2001b) Anaerobic conditions induce expression of polysaccharide intercellular adhesin in Staphylococcus aureus and Staphylococcus epidermidis . Infect Immun 69 : 4079-4085.

Götz, F. (2001) Genetic and biochemical analysis of the biosynthesis of the organge carotenoid staphyloxanthin of Staphylococcus aureus . In Microbial fundamentals of biotechnology . Braun, V. and Götz, F. (eds). Weinheim: WILEY-VCH Verlag GmbH, pp. 284-294.

Götz, F., and Jung, G. (2001) Biosynthesis of the lantibiotics epidermin and gallidermin. In Microbial fundamentals of biotechnology . Braun, V. and Götz, F. (eds). Weinheim: WILEY-VCH Verlag GmbH, pp. 52-92.

Götz, F., and Rosenstein, R. (2001) Staphylococcal lipases: Molecular characterization and use as an expression and secretion system. In Microbial fundamentals of biotechnology . Braun, V. and Götz, F. (eds). Weinheim: WILEY-VCH Verlag GmbH, pp. 238-248.

Gross, M., Cramton, S.E., Götz, F., and Peschel, A . (2001) Key role of teichoic acid net charge in Staphylococcus aureus colonization of artificial surfaces. Infect Immun 69 : 3423-3426.

Hille, M., Kies, S., Götz, F., and Peschel, A. (2001) Dual role of GdmH in producer immunity and secretion of the staphylococcal lantibiotics gallidermin and epidermin. Appl Environ Microbiol 67 : 1380-1383.

Kies, S., Otto, M., Vuong, C., and Götz, F. (2001) Identification of the sigB Operon in Staphylococcus epidermidis : Construction and Characterization of a sigB Deletion Mutant. Infect Immun 69 : 7933-7936.

Manosroi, J., Tayapiwatana, C., Götz, F., Werner, R.G., and Manosroi, A. (2001) Secretion of active recombinant human tissue plasminogen activator derivatives in Escherichia coli . Appl Environ Microbiol 67 : 2657-2664.

Otto, M., Echner, H., Voelter, W., and Götz, F. (2001) Pheromone cross-inhibition between Staphylococcus aureus and Staphylococcus epidermidis . Infect Immun 69 : 1957-1960.

Otto, M., and Götz, F. (2001) ABC transporters of staphylococci. Res Microbiol 152 : 351-356.

Rupp, M.E., Fey, P.D., Heilmann, C., and Götz, F. (2001) Characterization of the importance of Staphylococcus epidermidis autolysin and polysaccharide intercellular adhesin in the pathogenesis of intravascular catheter-associated infection in a rat model. J Infect Dis 183 : 1038-1042.

Staubitz, P., Peschel, A., Nieuwenhuizen, W.F., Otto, M., Götz, F., Jung, G., and Jack, R.W. (2001) Structure-function relationships in the tryptophan-rich, antimicrobial peptide indolicidin. J Peptide Sci 7 : 552-564.

Sturmfels, A., Götz, F., and Peschel, A. (2001) Secretion of human growth hormone by the food-grade bacterium Staphylococcus carnosus requires a propeptide irrespective of the signal peptide used. Arch Microbiol 175 : 295-300.

van Kampen, M.D., Rosenstein, R., Götz, F., and Egmond, M.R . (2001) Cloning, purification and characterisation of Staphylococcus warneri lipase 2. Biochim Biophys Acta 1544 : 229-241.

 
2000

Cramton, S.E., Schnell, N.F., Götz, F., and Brückner, R. (2000) Identification of a new repetitive element in Staphylococcus aureus . Infect Immun 68 : 2344-2348.

Götz, F., Heilmann, C., and Cramton, S.E. (2000) Molecular basis of catheter associated infections by staphylococci. Adv Exp Med Biol 485 : 103-111.

Götz, F., and Peters, G. (2000) Colonization of medical devices by coagulase-negative staphylococci. In Infections associated with indwelling medical devices . Waldvogel, F.A. and Bisno, A.L. (eds). Washington, D.C.: ASM, pp. 55 - 88.

Otto, M., and Götz, F. (2000) Analysis of quorum sensing activity in staphylococci by RP-HPLC of staphylococcal delta-toxin. Biotechniques 28 : 1088-1096.

Peschel, A., Vuong, C., Otto, M., and Götz, F. (2000) The D-alanine residues of Staphylococcus aureus teichoic acids alter the susceptibility to vancomycin and the activity of autolytic enzymes. Antimicrob Agents Chemother 44 : 2845-2847.

Rosenstein, R., and Götz, F. (2000) Staphylococcal lipases: biochemical and molecular characterization. Biochimie 82 : 1005-1014.

Rziha, H., Henkel, M., Cottone, R., Bauer, B., Auge, U., Götz, F., Pfaff, E., Rottgen, M., Dehio, C., and Buttner, M. (2000) Generation of recombinant parapoxviruses: non-essential genes suitable for insertion and expression of foreign genes. J Biotechnol 83 : 137-145.

Saenz, H.L., Augsburger, V., Vuong, C., Jack, R.W., Götz, F., and Otto, M. (2000) Inducible expression and cellular location of AgrB, a protein involved in the maturation of the staphylococcal quorum-sensing pheromone. Arch Microbiol 174 : 452-455.

Vuong, C., Götz, F., and Otto, M. (2000a) Construction and characterization of an agr deletion mutant of Staphylococcus epidermidis . Infect Immun 68 : 1048-1053.

Vuong, C., Saenz, H.L., Götz, F., and Otto, M. (2000b) Impact of the agr Quorum-Sensing System on Adherence to Polystyrene in Staphylococcus aureus . J Infect Dis 182 : 1688-1693.

Ziebuhr, W., Lössner, I., Rachid, S., Dietrich, K., Götz, F., and Hacker, J. (2000) Modulation of the polysaccharide intercellular adhesin (PIA) expression in biofilm forming Staphylococcus epidermidis . Analysis of genetic mechanisms. Adv Exp Med Biol 485 : 151-157.
 
1998/1999

Brötz, H., Josten, M., Wiedemann, I., Schneider, U., Götz, F., Bierbaum, G., and Sahl, H.G. (1998) Role of lipid-bound peptidoglycan precursors in the formation of pores by nisin, epidermin and other lantibiotics. Mol Microbiol 30 : 317-327.

Cramton, S.E., Gerke, C., Schnell, N.F., Nichols, W.W., and Götz, F. (1999) The intercellular adhesion (ica) locus is present in Staphylococcus aureus and is required for biofilm formation. Infect Immun 67 : 5427-5433.

Fey, P.D., Ulphani, J.S., Götz, F., Heilmann, C., Mack, D., and Rupp, M.E. (1999) Characterization of the relationship between Polysaccharide Intercellular Adhesin and hemagglutination in Staphylococcus epidermidis . J Infect Dis 179 : 1561-1564.

Gerke, C., Kraft, A., Süssmuth, R., Schweitzer, O., and Götz, F. (1998) Characterization of the N-acetylglucosaminyltransferase activity involved in the biosynthesis of the Staphylococcus epidermidis polysaccharide intercellular adhesin. J Biol Chem 273 : 18586-18593.

Götz, F., Verheij, H.M., and Rosenstein, R. (1998) Staphylococcal lipases: molecular characterisation, secretion, and processing. Chem Phys Lipids 93 : 15-25.

Götz, F. (1999) From new targets to new anti-infective substances. Nova Acta Leopoldina 307 : 281-294.

Heilmann, C., and Götz, F. (1998) Further characterization of Staphylococcus epidermidis transposon mutants deficient in primary attachment or intercellular adhesion. Zentralbl Bakteriol 287 : 69-83.

Kempf, M., Theobald, U., and Fiedler, H.-P. (1999) Economic improvement of the fermentative production of gallidermin by Staphylococcus gallinarum . Biotechnol. Letters 21 : 663-667.

Neubauer, H., Pantel, I., and Götz, F. (1998) Characterization of moeB - part of the molybdenum cofactor biosynthesis gene cluster in Staphylococcus carnosus . FEMS Microbiol Lett 164 : 55-62.

Neubauer, H., Pantel, I., and Götz, F. (1999a) Molecular characterization of the nitrite-reducing system of Staphylococcus carnosus . J Bacteriol 181 : 1481-1488.

Neubauer, H., Pantel, I., Lindgren, P.E., and Götz, F. (1999b) Characterization of the molybdate transport system ModABC of Staphylococcus carnosus . Arch Microbiol 172 : 109-115.

Ohlsen, K., Ziebuhr, W., Reichardt, W., Witte, W., Götz, F., and Hacker, J. (1999) Mobile elements, phages, and genomic islands of staphylococci and streptococci. In Pathogenicity islands and other mobile virulence elements . Kaper, J.B. and Hacker, J. (eds). Washington, D.C.: ASM.

Otto, M., Peschel, A., and Götz, F. (1998a) Producer self-protection against the lantibiotic epidermin by the ABC transporter EpiFEG of Staphylococcus epidermidis Tu3298. FEMS Microbiol Lett 166 : 203-211.

Otto, M., Süssmuth, R., Jung, G., and Götz, F. (1998b) Structure of the pheromone peptide of the Staphylococcus epidermidis agr system. FEBS Lett 424 : 89-94.

Otto, M., Süssmuth, R., Vuong, C., Jung, G., and Götz, F. (1999) Inhibition of virulence factor expression in Staphylococcus aureus by the Staphylococcus epidermidis agr pheromone and derivatives. FEBS Lett 450 : 257-262.

Pantel, I., Lindgren, P.E., Neubauer, H., and Götz, F. (1998) Identification and characterization of the Staphylococcus carnosus nitrate reductase operon. Mol Gen Genet 259 : 105-114.

Pantucek, R., Rosypalova, A., Doskar, J., Kailerova, J., Ruzickova, V., Borecka, P., Snopkova, S., Horvath, R., Götz, F., and Rosypal, S. (1998) The polyvalent staphylococcal phage phi 812: its host-range mutants and related phages. Virology 246 : 241-252.

Peschel, A., Otto, M., Jack, R.W., Kalbacher, H., Jung, G., and Götz, F. (1999) Inactivation of the dlt operon in Staphylococcus aureus confers sensitivity to defensins, protegrins, and other antimicrobial peptides. J Biol Chem 274 : 8405-8410.

Rosenstein, R., Futter-Bryniok, D., and Götz, F. (1999) The choline-converting pathway in Staphylococcus xylosus C2A: genetic and physiological characterization. J Bacteriol 181 : 2273-2278.

Simons, J.W., Götz, F., Egmond, M.R., and Verheij, H.M. (1998a) Biochemical properties of staphylococcal (phospho)lipases. Chem Phys Lipids 93 : 27-37.

Simons, J.W., van Kampen, M.D., Riel, S., Götz, F., Egmond, M.R., and Verheij, H.M. (1998b) Cloning, purification and characterisation of the lipase from Staphylococcus epidermidis - comparison of the substrate selectivity with those of other microbial lipases. Eur J Biochem 253 : 675-683.

Strauss, A., Thumm, G., and Götz, F. (1998) Influence of Lif, the lysostaphin immunity factor, on acceptors of surface proteins and cell wall sorting efficiency in Staphylococcus carnosus . J Bacteriol 180 : 4960-4962.

Wagner, E., Doskar, J., and Götz, F. (1998) Physical and genetic map of the genome of Staphylococcus carnosus TM300. Microbiology 144 : 509-517.

Ziebuhr, W., Krimmer, V., Rachid, S., Lößner, I., Götz, F., and Hacker, J. (1999) A novel mechanism of phase variation of virulence in Staphylococcus epidermidis : evidence for control of the polysaccharide intercellular adhesin synthesis by alternating insertion and excision of the insertion sequence element IS256. Mol Microbiol 32 : 345-356.

 
1996/1997

Bierbaum, G., Götz, F., Peschel, A., Kupke, T., van de Kamp, M., and Sahl, H.-G. (1996) The biosynthesis of the lantibiotics epidermin, gallidermin, Pep5 and epilancin K7. Antonie van Leeuwenhoek 69 : 119-127.

Fast, B., Lindgren, P., and Götz, F. (1996) Cloning, sequencing, and characterization of a gene ( narT ) encoding a transport protein involved in dissimilatory nitrate reduction in Staphylococcus carnosus . Arch Microbiol 166 : 361-367.

Geißler, S., Götz, F., and Kupke, T. (1996) Serine-protease EpiP from Staphylococcus epidermidis catalyzes the processing of the epidermin precursor peptide. J. Bacteriol. 178 : 284-288.

Gering, M., Götz, F., and Brückner, R. (1996) Sequence and analysis of the replication region of the Staphylococcus xylosus plasmid pSX267. Gene 182 : 117-122.

Heilmann, C., Gerke, C., Perdreau-Remington, F., and Götz, F. (1996a) Characterization of Tn917 insertion mutants of Staphylococcus epidermidis affected in biofilm formation. Infect. Immun. 64 : 277-282.

Heilmann, C., Schweitzer, O., Gerke, C., Vanittanakom, N., Mack, D., and Götz, F. (1996b) Molecular basis of intercellular adhesion in the biofilm-forming Staphylococcus epidermidis . Mol Microbiol 20 : 1083-1091.

Heilmann, C., Hussain, M., Peters, G., and Götz, F. (1997) Evidence for autolysin-mediated primary attachment of Staphylococcus epidermidis to a polystyrene surface. Mol Microbiol 24 : 1013-1024.

Jack, R., Götz, F., and Jung, G. (1997) Lantibiotics. In Products of secundary metabolism . Vol. 7. Kleinkauf, H. and von Döhren, H. (eds). Weinheim: VCH, pp. 323-368.

Kuipers, O.P., Bierbaum, G., Ottenwälder, B., Dodd, H.M., Horn, N., Metzger, J., Kupke, T., Gnau, V., Bengers, R., van den Bogaard, P., Kosters, H., Rollema, H.S., de Vos, W.M., Siezen, R.J., Jung, G., Götz, F., Sahl, H.-G., and Gasson, M.J. (1996) Protein engineering of lantibiotics. Antonie van Leeuwenhoek 69 : 161-169.

Kupke, T., and Götz, F. (1996a) Expression, purification, and characterization of EpiC, an enzyme involved in the biosynthesis of the lantibiotic epidermin, and sequence analysis of Staphylococcus epidermidis epiC mutants. J. Bacteriol. 178 : 1335-1340.

Kupke, T., and Götz, F. (1996b) Post-translational modification of lantibiotics. Antonie van Leeuwenhoek 69 : 139-150.

Kupke, T., and Götz, F. (1997a) The enethiolate anion reaction products of EpiD: pKa value of the enethiol side chain is lower than that of the thiol side chain of peptides. J. Biol. Chem. 272 : 4759-4762.

Kupke, T., and Götz, F. (1997b) In vivo reaction of affinity-tag-labelled epidermin precursor peptide with flavoenzyme EpiD. FEMS Microbiol. Lett. 153 : 25-32.

Neubauer, H., and Götz, F. (1996) Physiology and interaction of nitrate and nitrite reduction in Staphylococcus carnosus . J. Bacteriol. 178 : 2005-2009.

Pantucek, R., Götz, F., Doskar, J., and Rosypal, S. (1996) Genomic variability of Staphylococcus aureus and the other coagulase-positive Staphylococcus species estimated by macrorestriction analysis using pulsed-field gel electrophoresis. Int. J. System. Bacteriol. 46 : 216-222.

Peschel, A., and Götz, F. (1996) Analysis of the Staphylococcus epidermidis genes epiF , - E , and - G involved in epidermin immunity. J. Bacteriol. 178 : 531-536.

Peschel, A., Ottenwälder, B., and Götz, F. (1996) Inducible production and cellular location of the epidermin biosynthetic enzyme EpiB using an improved staphylococcal expression system. FEMS Microbiol Lett 137 : 279-284.

Peschel, A., Schnell, N., Hille, M., Entian, K.D., and Götz, F. (1997) Secretion of the lantibiotics epidermin and gallidermin: sequence analysis of the genes gdmT and gdmH , their influence on epidermin production and their regulation by EpiQ. Mol Gen Genet 254 : 312-318.

Simons, J.W., Adams, H., Cox, R.C., Dekker, N., Götz, F., Slotboom, A.J., and Verheij, H.M. (1996) The lipase from Staphylococcus aureus . Expression in Escherichia coli , large-scale purification and comparison of substrate specificity to Staphylococcus hyicus lipase. Eur J Biochem 242 : 760-769.

Sommer, P., Bormann, C., and Götz, F. (1997) Genetic and biochemical characterization of a new extracellular streptomycetes lipase from Streptomyces cinnamomeus . Appl. Environm. Microbiol. 63 : 3553-3560.

Strauss, A., and Götz, F. (1996) In vivo immobilization of enzymatically active polypeptides on the cell surface of Staphylococcus carnosus . Mol Microbiol 21 : 491-500.

Tesch, C., Nikoleit, K., Gnau, V., Götz, F., and Bormann, C. (1996) Biochemical and molecular characterization of the extracellular esterase from Streptomyces diastatochromogenes . J. Bacteriol. 178 : 1858-1865.

Thumm, G., and Götz, F. (1997) Studies on prolysostaphin processing and characterization of the lysostaphin immunity factor (Lif) of Staphylococcus simulans biovar staphylolyticus . Mol Microbiol 23 : 1251-1265.

von Eiff, C., Heilmann, C., Proctor, R.A., Woltz, C., Peters, G., and Götz, F. (1997) A site-directed Staphylococcus aureus hemB mutant is a small-colony variant which persists intracellularly. J Bacteriol 179 : 4706-4712.

Ziebuhr, W., Heilmann, C., Götz, F., Meyer, P., Wilms, K., Straube, E., and Hacker, J. (1997) Detection of the intercellular adhesion gene cluster (ica) and phase variation in Staphylococcus epidermidis blood culture strains and mucosal isolates. Infect Immun 65 : 890-896.

top