Publications

AG Autenrieth

 

Waidmann M, Bechtold O, Frick JS, Lehr HA, Schubert S, Dobrindt U, Loeffler J, Bohn E, Autenrieth IB (2003). Bacteroides vulgatus protects against Escherichia coli-induced colitis in gnotobiotic interleukin-2-deficient mice. Gastroenterology. 125(1), 162-177.

 

Becker, C., Wirtz, S., Blessing, M., Pirhonen, J., Strand, D., Bechtold, O., Frick, J., P.R. Galle, I.B.Autenrieth, M.F. Neurath. (2003) Constitutive p40 promoter activation and IL-23 production in the terminal ileum mediated by dendritic cells. J. Clin. Invest. 112:693-706

 

Frick, J.S., N. Zahir, M. Müller, F. Kahl, O. Bechtold, M. B. Lutz, C. J. Kirschning, J. Reimann, B. Jilge, E. Bohn, I. B. Autenrieth. (2006). Colitogenic and non-colitogenic commensal bacteria differentially trigger DC maturation and Th cell polarization: an important role for IL-6. Eur J Immunol. 36:1537-1547

 

Bohn, E., Bechtold, O., N. Zahir, J.-S. Frick, J. Reimann, B. Jilge and I. B. Autenrieth. (2006). Host gene expression in the colon of gnotobiotic interleukin-2-deficient mice colonized with commensal colitogenic or non-colitogenic bacterial strains: common patterns and bacteria strain specific signatures. Inflamm Bowel Dis. 12:853-862.

 

Autenrieth, S.E., I. Soldanova, R. Rösemann, D. Gunst, N. Zahir, M. Kracht, K. Ruckdeschel, H. Wagner, S. Borgmann, I. B. Autenrieth. (2007). Yersinia enterocolitica YopP inhibits MAP kinase-mediated antigen uptake in dendritic cells. Cell Microbiol. 9:425-437.

 

 

AG Braun

 

Stiefel, A., Mahren, S., Ochs, M., Schindler, P., Enz, S., Braun V.(2001). Control of the ferric citrate transport system of Escherichia coli: mutations in region 2.1 of the FecI extracytoplasmic-function sigma factor suppress mutations in the FecR transmembrane regulatory protein. J. Bacteriol. 183, 162-170.

 

Mahren, S., Enz, S. and Braun, V. (2002). Functional interaction of region 4 of the extracytoplasmic function sigma factor FecI with the cytoplasmic portion of the FecR transmembrane protein of the Escherichia coli ferric citrate transport system. J. Bacteriol 184, 3704-3711.

 

Mahren, S., and Braun, V. (2003). The FecI extracytoplasmic-funtion sigma factor of Escherichia coli interacts with the ß subunit of RNA Polymerase. J. Bacteriol. 185, 1796-1802.

 

Enz, S., Mahren, S., Menzel, C., Braun, V. (2003). Analysis of the ferric citrate transport gene promoter of Escherichia coli.J. Bacteriol. 185, 2387-2391.

 

Endriß, Fr., Braun, M., Killmann, H., Braun, V. (2003).Mutant analysis of the Escherichia coli FhuA protein reveals sites of FhuA acitity. J. Bacteriol. 185, 4683-4692.

 

Enz, S., Brand, H., Orellana, C., Mahren, S., Braun, V. (2003). Sites of interaction between the FecA and FecR signal transduction proteins of ferric citrate transport in Escherichia coli K-12. J. Bacteriol. 185, 3745-3752.

 

Braun, V., Mahren, S., Ogierman, M. (2003). Regulation of FecI-type ECF sigam factor by transmembrane signalling. Curr. Opin. Microbiol. 6: 173-180.

 

Braun, M., Endriss, F., Killmann, H., Braun, V. (2003). In vivo reconstitution of the FhuA transport protein of Escherichia coli K-12. J. Bacteriol. 185: 5508-5518.

 

Sauter, A., Howard, S. P., Braun, V. (2003). In vivo evidence for TonB dimerization. J Bacteriol. 185: 5747-5754

 

Sauter, S. R., Diekmann, S., Braun, V. (2003). Two-step purification of the outer membrane transporter and activator ShlB from Escherichia coli using internally His6-tagged constructs. J Chromo. 786: 33-37

 

Endriß, F., and Braun, V. (2004). Loop deletions indicate regions important for FhuA transport and receptor functions in Escherichia coli. J. Bacteriol. 186, 4818-4823.

 

Sauter, A., and Braun, V. (2004). Defined inactive FecA derivatives mutated in functional Domains of the outer membrane transport and signalling protein of Escherichia coli K-12. J. Bacteriol. 186, 5303-5310.

 

Braun, V. and Mahren S. (2005). Transmembrane transcriptional control (surface signalling) of the Escherichia coli Fec type. FEMS Microbiol. Rev.

 

Braun, V., Mahren, S., Sauter, A. (2006). Gene regulation by transmenbrane signaling. BioMetals 19: 103-113

 

Breidenstein, E., Mahren, S., Braun, V. (2006). Residues involved in FecR binding are localized on one side of the FecA signaling Domain in Escherichia coli. J. Bacteriol. 188:6440-6442

 

Braun, V., Mahren, S. (2006). Transfer of energy and information across the periplasm in iron transport and regulation. In: The periplasm (M. Ehrmann, ed.) ASM Press, pp 276-286

 

 

AG Fiedler

 

Maier, A., Riedlinger, J., Fiedler, H.-P., and Hampp, R. (2004). Actinomycetales bacteria from a spruce stand: characterization and effects on growth of root symbiotic and plant parasitic soil fungi in dual culture. Mycol. Progr. 3, 129-136.

 

Bringmann, G., Lang, G., Maksimenka, K., Hamm, A., Gulder, T.A.M., Dieter, A., Bull, A.T., Stach J.E.M., Kocher, N., Müller, W.E.G., and Fiedler, H.-P. (2005). Gephyromycin, the first bridged angucyclinone, from Streptomyces griseus strain NTK 14. Phytochem. 66: 1365-1372.

 

Riedlinger, J.; S.D. Schrey, M.T. Tarkka, R. Hampp, M. Kapur & H.-P. Fiedler (2006): Auxofuran, a novel metabolite that stimulates the growth of fly agaric, is produced by the mycorrhiza helper bacterium Streptomyces AcH 505. Appl. Environ. Microbiol. 72: 3550-3557

 

 

AG Götz

 

Kristian, S.A., Lauth, X., Nizet, V., Götz, F., Neumeister, B., Peschel, A., and Landmann, R. (2003) Alanylation of teichoic acids protects Staphylococcus aureus against Toll-like receptor 2-dependent host defense in a mouse tissue cage infection model. J Infect Dis 188: 414-423.

 

Wieland, H., Götz, F., and Neumeister, B. (2004) Phagosomal acidification is not a prerequisite for intracellular multiplication of Legionella pneumophila in human monocytes. J Infect Dis 189: 1610-1614.

 

Bera, A., Herbert, S., Jakob, A., Vollmer, W., and Götz, F. (2005) Why are pathogenic staphylococci so lysozyme resistant? The peptidoglycan O-acetyltransferase OatA is the major determinant for lysozyme resistance of Staphylococcus aureus. Mol Microbiol 55: 778-787.

 

Pelz, A., Wieland, K.P., Putzbach, K., Hentschel, P., Albert, K., and Götz, F. (2005) Structure and biosynthesis of staphyloxanthin from Staphylococcus aureus. J Biol Chem 280: 32493-32498.

 

Resch, A., Fehrenbacher, B., Eisele, K., Schaller, M., and Götz, F. (2005a) Phage release from biofilm and planktonic Staphylococcus aureus cells. FEMS Microbiol Lett 252: 89-96.

 

Resch, A., Rosenstein, R., Nerz, C., and Götz, F. (2005b) Differential gene expression profiling of Staphylococcus aureus cultivated under biofilm and planktonic conditions. Appl Environ Microbiol 71: 2663-2676.

 

Resch, A., Leicht, S., Saric, M., Pasztor, L., Jakob, A., Götz, F., and Nordheim, A. (2006a) Comparative proteome analysis of Staphylococcus aureus biofilm and planktonic cells and correlation with transcriptome profiling. Proteomics 6: 1867-1877.

 

Resch, A., Leicht, S., Saric, M., Pasztor, L., Jakob, A., Götz, F., and Nordheim, A. (2006b) Comparative proteome analysis of Staphylococcus aureus biofilm and planktonic cells and correlation with transcriptome profiling-correction. Proteomics 6: 2327.

 

Voggu, L., Schlag, S., Biswas, R., Rosenstein, R., Rausch, C., and Götz, F. (2006) Microevolution of cytochrome bd oxidase in staphylococci and Its implication in resistance to respiratory toxins released by Pseudomonas. J Bacteriol 188: 8079-8086.

 

Bera, A., Biswas, R., Herbert, S., and Götz, F. (2006) The presence of peptidoglycan O-acetyltransferase in various staphylococcal species correlates with lysozyme resistance and pathogenicity. Infect Immun 74: 4598-4604.

 

Biswas, R., Voggu, L., Simon, U.K., Hentschel, P., Thumm, G., and Götz, F. (2006) Activity of the major staphylococcal autolysin Atl. FEMS Microbiol Lett 259: 260-268.

 

Clauditz, A., Resch, A., Wieland, K.P., Peschel, A., and Götz, F. (2006) Staphyloxanthin plays a role in the fitness of Staphylococcus aureus and its ability to cope with oxidative stress. Infect Immun 74: 4950-4953.

 

Bera, A., Biswas, R., Herbert, S., Kulauzovic, E., Weidenmaier, C., Peschel, A., and Götz, F. (2007) Influence of wall teichoic acid on lysozyme resistance in Staphylococcus aureus. J Bacteriol 189: 280-283.

 

 

AG Hantke

 

Zhu, M., Valdebenito, M., Winkelmann, G., and Hantke, K. (2005). Fuctions of the siderophore esterases IroD and IroE in iron-salmochelin utilization. Microbiol. 151: 2363-2372

 

 

AG Hampp

 

Maier, A., Riedlinger, J., Fiedler, H.-P., Hampp, R. (2004). Actinomycetales bacteria from a spruce stand: characterization and effects on growth of root symbiotic and plant parasitic soil fungi in dual culture. Mycologycal Progress 3(2), 129-136

 

Hampp, R., Maier, A. (2004). Interaction between soil bacteria and ectomycorrhiza-forming fungi. Plant surface microbiology, Springer-Verlag Berlin Heidelberg, 197-210

 

Hampp, R., Schrey, S., Tarkka, M. (2005). Die Rhizosphäre: Koexistenz im Wurzelraum.
BIOforum 1, 2-3

 

Schrey SD, Schellhammer M, Ecke M, Hampp R, Tarkka MT (2005) Mycorrhiza helper bacterium Streptomyces AcH 505 induces differential gene expression in the ectomycorrhizal fungus Amanita muscaria. New Phytologist 168: 205-216

 

Tarkka MT, Schrey S, Nehls U (2006) The alpha-tubulin gene AmTuba1: a marker for rapid mycelial growth in the ectomycorrhizal basidiomycete Amanita muscaria. Current Genetics 49: 294-301

 

Riedlinger J, Schrey SD, Tarkka MT, Hampp R, Kapur M, Fiedler HP (2006) Auxofuran, a novel metabolite that stimulates the growth of fly agaric, is produced by the mycorrhiza helper bacterium Streptomyces 
strain AcH 505. Applied and Environmental Microbiology 72: 3550-3557

 

Lehr NA, Schrey SD, Bauer R, Hampp R, Tarkka MT (2007) Suppression of 
plant defence response by a mycorrhiza helper bacterium. New 
Phytologist doi: 10.1111/j.1469-8137.2007.02021.

 

 

AG Peschel

 

Collins LV, Kristian SA, Weidenmaier C, Faigle M, Van Kessel KP, Van Strijp JA, Götz F, Neumeister B, Peschel A (2002) Staphylococcus aureus strains lacking D-alanine modifications of teichoic acids are highly susceptible to human neutrophil killing and are virulence attenuated in mice. J Infect Dis 186:214-219

 

Dürr M, Peschel A (2002) Chemokines meet defensins - the merging concepts of chemoattractants and antimicrobial peptides in host defense. Infect Immun 70:6515-6517

 

Somerville GA, Cockayne A, Dürr M, Peschel A, Otto M, Musser JM (2003) Synthesis and deformylation of Staphylococcus aureus delta-toxin are linked to tricarboxylic acid cycle activity. J Bacteriol 185:6686-6694

 

Kristian SA, Dürr M, Van Strijp JA, Neumeister B, Peschel A (2003) MprF-mediated lysinylation of phospholipids in Staphylococcus aureus leads to protection against oxygen-independent neutrophil killing. Infect Immun 71:546-549

 

Weidenmaier C, Kristian SA, Peschel A (2003) Bacterial resistance to antimicrobial host defenses - an emerging target for novel antiinfective strategies? Curr Drug Targets 4:643-649

 

Staubitz P, Kristian SA, Weidenmaier C, Dürr M , Kraus D, Fedtke I, Peschel A (2003) Wie bakterielle Erreger die angeborene Abwehr umgehen molekularen Grundlagen am Beispiel von Staphylococcus aureus. Hygiene und Mikrobiol 7:65-68.

 

Vuong C, Dürr M, Carmody AB, Peschel A, Klebanoff SJ, Otto M (2004) Regulated expression of pathogen-associated molecular pattern molecules in Staphylococcus epidermidis: quorum-sensing determines pro-inflammatory capacity and production of phenol-soluble modulins. Cell Microbiol 6:753-759

 

Weidenmaier C, Kokai-Kun JF, Kristian SA, Chanturyia T, Kalbacher H, Gross M, Nicholson G, Neumeister B, Mond JJ, Peschel A (2004) Role of teichoic acids in Staphylococcus aureus nasal colonization, a major risk factor in nosokomial infections. Nat Med 10:243-245

 

Weidenmaier C, Peschel A, Xiong YQ, Kristian SA, Dietz K, Yeaman MR, Bayer AS (2005) Lack of wall teichoic acids in Staphylococcus aureus leads to reduced interactions with endothelial cells and to attenuated virulence in a rabbit model of endocarditis. J Infect Dis 191:1771-1777

 

Kristian SA, Datta V, Weidenmaier C, Kansal R, Fedtke I, Peschel A, Gallo RL, Nizet V (2005) D-alanylation of teichoic acid promotes group A Streptococcus antimicrobial peptide resistance, neutrophil survival, and epithelial cell invasion. J Bacteriol 187:6719-6725

 

Weidenmaier C, Peschel A, Kempf VA, Lucindo N, Yeaman MR, Bayer AS (2005) DltABCD- and MprF-mediated cell envelope modifications of Staphylococcus aureus confer resistance to platelet microbicidal proteins and contribute to virulence in a rabbit endocarditis model. Infect Immun 73:8033-8038

 

Dürr M, Kristian SA, Otto M, Matteoli G, Margolis PS, Trias J, Van Kessel KP, Van Strijp JA, Bohn E, Landmann R, Peschel A (2006) Neutrophil chemotaxis by pathogen-associated molecular patterns - formylated peptides are crucial but not the sole neutrophil attractants produced by Staphylococcus aureus. Cell Microbiol 8:207-217

 

Bera A, Biswas R, Herbert S, Kulauzovic E, Weidenmaier C, Peschel A, Götz F (2007) Wall teichoic acids and O-acetylation are two factors that contribute to lysozyme resistance in Staphylococcus aureus. Infect Immun In press

 

 

AG Wohlleben

 

E. Heinzelmann, G. Kienzlen, S. Kaspar, J. Recktenwald, W. Wohlleben und D. Schwartz (2001).
The phosphinomethylmalate isomerase gene pmi, encoding an aconitase-like enzyme, is involved in the synthesis of phosphinothricin tripeptide in Streptomyces viridochromogenes.
Appl. Environ. Microbiol. 67, 3603-3609

 

J. Recktenwald, R. Shawky, O. Puk, F. Pfennig, U. Keller, W. Wohlleben und S. Pelzer, (2002).
Nonribosomal biosynthesis of vancomycin-type antibiotics: a heptapeptide backbone and eight peptide synthetase modules. Microbiology 148, 1105-1118

 

E. Heinzelmann, S. Berger, O. Puk, B. Reichenstein, W. Wohlleben, and D. Schwartz, (2003).
A glutamate mutase is involved in the biosynthesis of the lipopeptide antibiotic friulimicin in Actinoplanes friuliensis. Antimicrob. Agents Chemother. 47, 447-457

 

D. Schwartz, S. Berger, E. Heinzelmann, K. Muschko, K. Welzel, and W. Wohlleben, (2004):
The biosynthetic gene cluster of the herbicide phosphinothricin tripeptide from Streptomyces viridochromogenes Tü494. Appl. Environ. Microbiol. 70, 7093-7102

 

Heinzelmann, E., Berger, S., Müller, C., Härtner, T., Poralla, K., Wohlleben, W., and Schwartz, D, (2005). An acyl-CoA dehydrogenase is involved in the formation of the cis3 double bond in the acyl residue of the lipopeptide antibiotic friulimicin in Actinoplanes friuliensis.
Microbiology 151, 1963-1974

 

D. Schwartz, N. Grammel, E. Heinzelmann, U. Keller, and W. Wohlleben, (2005).
Phosphinothricin Tripeptide Synthetases in Streptomyces viridochromogenes Tü494.
Antimicrob. Agents Chemother. 49, 4598-4607

 

R. Shawky, O. Puk, A. Wietzorrek, S. Pelzer, E. Takano, W. Wohlleben, and E. Stegmann:
The border sequence of the balhimycin biosynthesis gene cluster from Amycolatopsis balhimycina contains bbr, encoding a StrR-like pathway-specific regulator.
J. Mol Microbiol. Biotechnol. 171, in press

 

 

Publications of former research groups

 

 

AG Neumeister

 

Neumeister, B., Rammensee, H.G., Spitznagel, D., Mainka, A., Ograbek, A., Wieland, H., Mannowetz, N., and Faigle, M. (2005) Legionella pneumophila down-regulates MHC class I expression of human monocytic host cells and thereby inhibits T cell activation. CMLS 62;578-588.

 

Wieland, H., Götz, F., and Neumeister, B. (2004). Phagosomal acidification is not a prerequisite for intracellular multiplication of Legionella pneumophila in human monocytes. J Infect Dis 189, 1610-1614.

 

Kristian, S. A., Golda, T., Ferracin, F., Cramton, S. E., Neumeister, B., Peschel, A., Götz, F., and Landmann, R. (2004). The ability of biofilm formation does not influence virulence of Staphylococcus aureus and host response in a mouse tissue cage infection model. Microb Pathog 36, 237-245.

 

 

AG Oberwinkler

 

Simon UK, Bauer R, Oberwinkler F. (2004). The unique cellular interaction between the leaf pathogen Cymadothea trifolii and Trifolium repens. Mycologia 96 (6), 1210-1218.

 

Simon UK, Bauer R, Rioux D, Simard M, Oberwinkler F. (2005a). The intercellular biotrophic leaf pathogen Cymadothea trifolii locally degrades pectins, but not cellulose or xyloglucan in cell walls of Trifolium repens. New Phytologist 165, 243-260.

 

Simon UK, Bauer R, Rioux D, Simard M, Oberwinkler F. (2005b). The vegetativelife cycle of the clover pathogen Cymadothea trifolii as seen in the electron microscope. Mycological Research 109 (7), 764-778.

 

 

AG Rammensee

 

Carralot JP, Probst J, Hoerr I, Scheel B, Teufel R, Jung G, Rammensee HG, Pascolo S, (2004). Polarization of immunity induced by direct injection of naked sequence-stabilized mRNA vaccines. Cell Mol Life Sci. 61:2418-2424.

 

Probst J, Blumenthal SG, Tenzer S, Weinschenk T, Dittmer J, Schoor O, Six A, Rammensee HG, Pascolo S, (2004). A conserved sequence in the mouse variable T cell receptor alpha recombination signal sequence 23-bp spacer can affect recombination. Eur J Immunol. 34:2179-2190.

 

Scheel B, Braedel S, Probst J, Carralot JP, Wagner H, Schild H, Jung G, Rammensee HG, Pascolo S, (2004). Immunostimulating capacities of stabilized RNA molecules. Eur J Immunol. 34:537-547.

 

Scheel B, Teufel R, Probst J, Carralot JP, Geginat J, Radsak M, Jarrossay D, Wagner H, Jung G, Rammensee HG, Hoerr I, Pascolo S, (2005). Toll-like receptor-dependent activation of several human blood cell types by protamine-condensed mRNA. Eur J Immunol 35:1557-1566.