Prof. Dr. Frank Böckler

Prof. Dr. Frank M. Böckler



Molekulares Design & Pharmazeutische Biophysik

Lehrstuhl Pharmazeutische Chemie

Pharmazeutisches Institut

Eberhard Karls Universität Tübingen

Auf der Morgenstelle 8 (Haus B)

D - 72076 Tübingen



Tel.:    +49 7071 29 74567

Fax:    +49 7071 29 5637

E-Mail:  Frank.Boeckler[at]


Frank M. Boeckler received his Ph.D. in Medicinal Chemistry at the University of Erlangen (Germany) in 2004 under supervision of Prof. Peter Gmeiner. He specialized in computational chemistry and drug design, ranging from QM methods to in silico screening. In 2006, he joined Prof. Sir Alan R. Fersht at the MRC Center for Protein Engineering in Cambridge/UK as Marie Curie fellow and discovered there p53 mutant stabilizers as potential new cancer therapeutics. While working in Cambridge at the interface of experiment and theory, he focused on molecular biology and biophysics. In 2008, he was appointed as Professor (W2tt) for Bioanalytics at Ludwig-Maximilians University (LMU) Munich. In 2010, he moved to Eberhard Karls University Tuebingen as Professor for Medicinal Chemistry/Drug Design, where he now heads the Laboratory for Molecular Design & Pharmaceutical Biophysics. His work is dedicated to understanding molecular interactions as the foundation for chemical biology and drug research and to apply theoretical and biophysical methods to cancer research, particularly, for targeting the extensive p53 network.

European Federation for Medicinal Chemistry:

Prof. Dr. Frank Boeckler was announced to be the winner of the EFMC Prize for Young Medicinal Chemists in Academia 2016.

JMC Perspective:

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Frank M Boeckler

Most read paper (in Journal of Medicinal Chemistry 2013):

Principles and Applications
of Halogen Bonding
in Medicinal Chemistry
and Chemical Biology

Rainer Wilcken,
Markus O. Zimmermann,
Andreas Lange,
Andreas C. Joerger,
and Frank M. Boeckler

2013, 56 (4), pp 1363–1388

DOI: 10.1021/jm3012068

(freely available online!)