Modelling group
at the Department of Medical Biometry, University of Tübingen
français deutsch
About us

Research
Influenza
Emerging diseases
Smallpox
Measles
Poliomyelitis
Malaria
Onchocerciasis
  Introduction
  Infection
       Summary
       Acquisition
       Immuno-suppression
       Infection rate
  Nodules
       Summary
       Nodule formation
       Palpation
       Prevalence
       Data
  Infectious larvae
  Microfilariae
       Summary
       Reproduction
  Diagnosis
       Summary
       Palpation
  Regulation
       Summary
       Biology
       Data
       Eradicability
  Life cycle
  Glossary
Filariases
Leishmaniasis
Haemophilus
Pneumococci
Others

Methods

Publications

Public Relations

Impressum

Vector stages (L3) of Onchocerca volvulus

Kumba
Cameroon Rainforest (Photo: M. Eichner) 		At the Institut de Recherche Medicale et des Plantes Medicinales (I.M.P.M.) in Kumba, Kamerun, Martin Eichner studied the development of Onchocerca volvulus larvae following intrathoracic injection of microfilariae in the vector fly. huts
Cameroon Savanna (Photo: M. Eichner)

As the source of infection, the number of injected microfilariae per fly and the exact time of infection were known, it was possible
(1) to attribute the exact ages to each developing larval stage.



(2) to determine length measurements which allow to differentiate the infectious larvae of the highly eye-pathogenic Savannah strain from those of the less severe forest strain, and from zoonotic filariae.



(3) to show that the decline in the number of invectious larvae per fly is not caused by a loss of larvae during sugar feeding of the fly (as was broadly assumed), but by increased vector mortality induced by the infectious larvae.

Responsible for this page: Prof. Dr. M. Eichner
Webmaster: Prof. Dr. M. Eichner (last change of this page on 13 July 2009)
Cooperation with: Dr. A. Renz, Institute for Tropical Medicine, University of Tübingen, Germany
Prof. P. Wenk, Institute for Tropical Medicine, University of Tübingen, Germany
Dr. P. Enyong, Institut de Recherche Medicale et des Plantes Medicinales (I.M.P.M.), Kumba, Cameroon
Disclaimer: Eberhard-Karls-University Tübingen, Tübingen University Hospital, the Department for Medical Biometry (IMB), and the authors of this page disclaim all liability for the content of any page referenced by hyper-link from this page

You are the  th visitor of our pages.