1. Explain the stereochemical outcome of the following reactions. Try to draw a suitable transition state model that leads to the major product. Keywords: Felkin-Anh, E/Z-Enolates, Zimmerman-Traxler. [Reiser, O. Chem. Rev. 1999, 1191]
2. Explain the stereochemical outcome of the following reactions. Try to draw a suitable transition state model that leads to the major product. Keywords: chelation control, open vs. closed transition states [Reiser, O. Chem. Rev. 1999, 1191; Keck, G. Org. Lett. 2001, 3, 707 (1); JACS 1996, 118, 4322 (3)].
3. Explain the stereochemical outcome of the following aldol reactions. Try to draw a suitable transition state model that leads to the major product. Keywords: Zimmerman-Traxler, Roush-model, anti-Felkin-Anh, open transition state [Abiko, A. Org. Synth. 2002, 79, 116-124 (1); Evans, D. A. JACS 2003, 125, 10893 (2); Perkins, M. V. Org. Lett. 2002, 4, 1655 (3); Danishefsky, S. JACS 1999, 121, 7050 (4); Mulzer, J. JOC 2000, 65, 7456 (5); Schinzer, D. Chem. Eur. J. 1999, 5, 2483 (6)]
4. Explain the stereochemical outcome of the following aldol reactions. Try to draw a suitable transition state model that leads to the major product. [Crimmins, M. T. JOC 2001, 66, 894 (1,2); Evans, D. A. JACS 1990, 112, 866 (3,4); Paterson, I. Tet. Lett. 2001, 42, 1187 (5); Paterson, I. Synthesis 1998, 639 (6)]
