Subproject D08: Elucidating the native function and signalling components of the cell death executioners Bs3 and Bs4C
Principal Investigators:
Prof. Dr. Thomas Lahaye
Universität Tübingen
ZMBP, General Genetics
Auf der Morgenstelle 32
72076 Tübingen
+49 7071 - 2972076
Fax +49 7071 - 295042
thomas.lahaye@zmbp.uni-tuebingen.de
Summary:
Preliminary work in the project resulted in identification of genes that are required for cell death executed by the pepper resistance genes Bs3 and/or Bs4C. We will characterize the identified signaling components at the molecular level and establish testable working models that explain how Bs3/Bs4C expression translates into cell death. Moreover we will study the proposed native function of Bs3/Bs4C as transcriptionally-controlled regulators of developmental programmed cell death.